Concepedia

Design, synthesis, and structure–activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis

Weiguo Liu, Steve Chen, James F. Dropinski, Lawrence F. Colwell, Michael H. Robins, Michael J. Szymonifka, Nancy S. Hayes, Neelam Sharma, Karen L. MacNaul, Melba Hernandez,

Bioorganic & Medicinal Chemistry Letters · 2005 · 27 citations · 12 references

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12

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi et al. · Nature · 1996 · 1.7K citations

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Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway

Jürgen M. Lehmann, Steven A. Kliewer, Linda B. Moore et al. · Journal of Biological Chemistry · 1997 · 1.2K citations · Full text

, , +17

LXR, a nuclear receptor that defines a distinct retinoid response pathway.

P J Willy, Kazuhiko Umesono, Estelita S. Ong et al. · Genes & Development · 1995 · 1.1K citations · Full text

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Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ

Bethany A. Janowski, Michael J. Grogan, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1999 · 937 citations

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27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells

Xuan Fu, John G. Menke, Yu‐Li Chen et al. · Journal of Biological Chemistry · 2001 · 575 citations · Full text

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