YM-47522, a Novel Antifungal Antibiotic Produced by Bacillus sp. II. Structure and Relative Stereochemistry.

Abstract

YM-47522 (1) was isolated from the fermentation broth of Bacillus sp. YL-03709B as an antifungal antibiotic. The structure of 1 was elucidated by spectroscopic analyses. YM-47522 (1) consisted of C13 carboxylic acid amide and cinnamate moieties. The relative stereochemistry was also proposed on the basis of chemical transformation into a 1,3-diol acetonide and its NMR data.