Journal of Studies on Alcohol · 1977 · 53 citations · 0 references
MedicinePharmacologyNeurochemistryPsychopharmacologySubstance Use DisordersAlcohol MetabolismAlcohol PharmacologyAlcohol-drug InteractionsBlood Alcohol ConcentrationMonoamine NeurochemistrySubstance IntoxicationAcetaldehyde EffectsAcetaldehyde OxidationAlcohol MetabolitesDopaminergic System EffectsNeuroadaptive Responses To Alcohol
The intensity of the disulfiram-alcohol reaction is found to depend on the blood acetaldehyde level, a disulfiram-induced predisposition reflected by alkalosis, and an individual predisposition reflected by dopamine-beta-hydroxylase activity.