Antimicrobial Resistance Profiles of Urinary<i>Escherichia Coli</i>Isolates

Abstract

Current knowledge on antimicrobial susceptibility pattern of uropathogens is necessary for appropriate therapy. The objective of this study was to investigate antibiotic susceptibility of 28 clinically isolated strains Escherichia coli, associated with different urinary tract infections. Lowest susceptibility detected was for betalactams ampicillin and ampicillin/sulbactam. High susceptibility was detected for aminoglycoside antibiotics. Approximately half of investigated strain showed multidrug resistance profiles. Plasmid content of E. coli isolates was investigated and participation of detected plasmids in drug resistance was discussed. Our data show the high level of antimicrobial resistance and extended spectrum b—lactamases (ESBL) production amongst the uropathogens causing urinary tract infection.