Alternative splicing and gene duplication are inversely correlated evolutionary mechanisms

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

Jason M. Johnson, John C. Castle, Philip W. Garrett-Engele et al. · Science · 2003 · 1.4K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Automatic clustering of orthologs and in-paralogs from pairwise species comparisons

Maido Remm, Christian E. V. Storm, Erik L. L. Sonnhammer · Journal of Molecular Biology · 2001 · 1.2K citations

Life Sciences, Bioinformatics, Evolutionary Biology +14

The evolution of functionally novel proteins after gene duplication

A. Hughes · Proceedings of the Royal Society B Biological Sciences · 1994 · 1K citations

Life Sciences, Biology, Evolutionary Biology +16

Alternative splicing and genome complexity

David Brett, Heike Pospisil, Juan Valcárcel et al. · Nature Genetics · 2001 · 542 citations

Life Sciences, Genetics, Molecular Biology +11

Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

Barmak Modrek, Christopher J. Lee · Nature Genetics · 2003 · 523 citations

Life Sciences, Genetics, Molecular Genetics +7