Bryostatin, a non-phorbol macrocyclic lactone, activates intact human polymorphonuclear leukocytes and binds to the phorbol ester receptor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Isolation of mononuclear cells and granulocytes from human blood.

Arne Bøyum · Scandinavian Journal of Clinical and Laboratory Investigation · 1968 · 9.6K citations

Life Sciences, Cell Biology, Immunology +7

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

Marco Castagna, Yoshimi Takai, Kozo Kaibuchi et al. · Journal of Biological Chemistry · 1982 · 4.8K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT

Bernard Babior, Ruby S. Kipnes, John T. Curnutte · Journal of Clinical Investigation · 1973 · 2.9K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

Andrew S. Kraft, Wayne B. Anderson · Nature · 1983 · 1.3K citations

Life Sciences, Biochemistry, Cell Biology +12