Concepedia

Identification of a urinary metabolite of perazine as a piperazine-2,5-dione derivative

D. Krauss, Walter Otting, Ursula Breyer

Journal of Pharmacy and Pharmacology · 1969 · 17 citations · 7 references

DOI

Concepts

Abstract

Abstract A non-basic perazine metabolite has been isolated from the urine of schizophrenic patients ingesting perazine. Identification of this compound as 10-[3‘-(2“,5”-dioxo-4“-methyl-piperazinyl)-propyl]-phenothiazine sulphoxide was achieved using ultraviolet, infrared, nuclear magnetic resonance and mass spectroscopy.

References

7

Studies in mass spectrometry—XV

J. H. Bowie, Dudley H. Williams, S.‐O. LAWESSON et al. · Tetrahedron · 1966 · 103 citations

, , +11

Urinary metabolites of 10-[3'-(4″-methyl-piperazinyl)-propyl]-phenothiazine (perazine) in psychiatric patients—I

Ursula Breyer · Biochemical Pharmacology · 1969 · 38 citations

, , +11

Studies in the biochemistry of micro-organisms. 111. The production of <scp>l</scp>-phenylalanine anhydride (<i>cis</i>-<scp>l</scp>-3, 6-dibenzyl-2, 5-dioxopiperazine) by <i>Penicillium nigricans</i> (Bainier) Thom

J. H. Birkinshaw, YS MOHAMMED · Biochemical Journal · 1962 · 32 citations · Full text

, , +6

Identification of the Diketopiperazine of Histidylproline in Human Urine

Thomas L. Perry, Keith Richardson, Shirley Hansen et al. · Journal of Biological Chemistry · 1965 · 30 citations · Full text

, , +4

Urinary metabolites of 10-[3?-(4?-methyl-piperazinyl)-propyl]-phenothiazine (perazine) in psychiatric patients

K Kanig, Ursula Breyer · Psychopharmacology · 1969 · 18 citations

, , +13