JAMA · 1966 · 29 citations · 5 references
MedicineCardiologySurgeryCardiothoracic SurgeryDigital TherapeuticsPostoperative Cardiac CareSurgical ProphylaxisDigitalis ToxicityExperimental StudiesProphylactic Use
After balancing the high toxic potential of digitalis, particularly during the immediate postoperative period, against benefits suggested by experimental studies but unproved under clinical conditions, the authors reach the conclusion that at the present time neither the routine use of digitalis in open-heart surgery nor its prophylactic use in general is justified.
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Eugene Braunwald, Robert D. Bloodwell, Leon I. Goldberg et al. · Journal of Clinical Investigation · 1961 · 258 citations · Full text
Arrhythmias after cardiac surgery. I. Uncomplicated atrial septal defect
Robert W. Popper, J. Knott, Arthur Selzer et al. · American Heart Journal · 1962 · 30 citations
Medicine, Cardiology, Surgery +14