Publication | Open Access
ON THE RIBONUCLEIC ACID SYNTHESIZED IN A CELL-FREE SYSTEM OF ESCHERICHIA COLI
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1962
Year
E. ColiEngineeringMolecular BiologySynthetic CircuitGene TranscriptionProtein SynthesisBiosynthesisRna ProcessingRna Structure PredictionRna BiologyDna ReplicationE. Coli CellsMolecular MicrobiologyGene ExpressionProtein BiosynthesisNatural SciencesSynthesized RnaNucleic Acid BiochemistrySynthetic BiologyGenetic EngineeringMicrobiologySystems Biology
This article describes experiments in which RNA is synthesized in an in vitro system derived from E. coli. The synthesized RNA is found to behave essentially like the undegraded messenger-RNA detectable in growing E. coli cells. The ability to synthesize this process was crucial in deciphering the genetic code.
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