Role of Differential Expression of Streptococcal Arginine Deiminase in Inhibition of <i>fimA</i> Expression in <i>Porphyromonas gingivalis</i>

Abstract

Streptococcus cristatus ArcA inhibits production of a major adhesin, FimA, in Porphyromonas gingivalis, a primary periodontal pathogen. In this study, we demonstrate the differential expression of arcA in two streptococcal species. The expression level of arcA in streptococci appears to be controlled by both cis and trans elements.