Malignant Boutonneuse fever with multiple organ failure: a three-case series

Abstract

Rickettsia conorii infection, the agent of Boutonneuse fever, presents usually in a form considered benign, with serious complications in less than 10% of patients. Its mechanism of infection consists of vascular endothelial invasion by the microorganism and subsequent vasculitis and tissue necrosis. The process is usually localized or limited to the skin but can progress with malignant severe systemic involvement [1,2].