Pseudo-Gaucher cell in IgMk plasmacytoid lymphoma

Abstract

Cells resembling those of Gaucher's disease were found on imprints of a lymph node from a patient with a plasmacytoid lymphoma. These cells contained nonspecific esterase, and electron-dense crystal-like structures. Associated plasma cells stained positively with anti-kappa and anti-mu sera but few macrophages were stained. The resemblance of these macrophages to Gaucher cells was due to the crystal-like inclusions that probably represented altered immunoglobulin.