The Effect of Radiofrequency Catheter Ablation on Myocardial Creatine Kinase Activity

Abstract

Creatine kinase activity in myocardial tissue is significantly diminished within the RF lesion. Creatine kinase activity is not stable at temperatures above 65 degrees C, which are routinely achieved within the central zone of RF ablation, and is unaffected by RF current in the absence of hyperthermia. Measurements of serum creatine kinase activity after RF catheter ablation may significantly underestimate the volume of myocardial injury.