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Novel selective androgen receptor modulators: SAR studies on 6-bisalkylamino-2-quinolinones

Arjan van Oeveren, Mehrnoush Motamedi, Esther Martinborough, Shuo Zhao, Yixing Shen, Sarah J. West, William Y. Chang, Adam Kallel, Keith B. Marschke, Francisco J. López,

Bioorganic & Medicinal Chemistry Letters · 2007 · 27 citations · 7 references

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7

An Orally Active Selective Androgen Receptor Modulator Is Efficacious on Bone, Muscle, and Sex Function with Reduced Impact on Prostate

Jeffrey N. Miner, William Y. Chang, Mark S. Chapman et al. · Endocrinology · 2006 · 136 citations

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Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators

Craig Marhefka, Wenqing Gao, Kiwon Chung et al. · Journal of Medicinal Chemistry · 2004 · 136 citations · Full text

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Pharmacological and X-Ray Structural Characterization of a Novel Selective Androgen Receptor Modulator: Potent Hyperanabolic Stimulation of Skeletal Muscle with Hypostimulation of Prostate in Rats

Jacek Ostrowski, Joyce E. Kuhns, John A. Lupisella et al. · Endocrinology · 2006 · 129 citations

, , +17

Bone Anabolic Effects of S-40503, a Novel Nonsteroidal Selective Androgen Receptor Modulator (SARM), in Rat Models of Osteoporosis

Keigo Hanada, Kazuyuki Furuya, Noriko Yamamoto et al. · Biological and Pharmaceutical Bulletin · 2003 · 122 citations · Full text

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Discovery of 6-<i>N,N</i>-Bis(2,2,2-trifluoroethyl)amino- 4-trifluoromethylquinolin-2(1<i>H</i>)-one as a Novel Selective Androgen Receptor Modulator

Arjan van Oeveren, Mehrnouch Motamedi, Neelakandha S. Mani et al. · Journal of Medicinal Chemistry · 2006 · 79 citations · Full text

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