Luteal function and oestrus in gilts treated with a synthetic analogue of prostaglandin F-2α (ICI 79,939) at various times during the oestrous cycle

Abstract

Treatment of cattle with various doses of prostaglandin (PG) F-2α by subcutaneous injection (Lauderdale, 1972) or by nonsurgical intrauterine injection (Rowson, Tervit & Brand, 1972; Liehr, Marion & Olson, 1972; Louis, Hafs & Morrow, 1972) induces luteal regression and allows oestrus to occur if initiated after Days 3 or 4 of the oestrous cycle. The oestrous cycle of the mare can also be shortened by administration of PGF-2α (Douglas & Ginther, 1972). Because the presence of the uterus is required for normal cyclic function in the pig (Anderson, Bland & Melampy, 1969), the effects of a synthetic analogue of PGF-2α, ICI 79,939, on luteal function and oestrus in gilts was investigated.