Concepedia

The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models

Wei Wang, Jiang‐Jiang Qin, Sukesh Voruganti, Kalkunte S. Srivenugopal, Subhasree Nag, Shivaputra A. Patil, Horrick Sharma, Ming‐Hai Wang, Hui Wang, John K. Buolamwini,

Nature Communications · 2014 · 99 citations · 32 references

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32

Cancer statistics, 2014

Rebecca L. Siegel, Jiemin Ma, Zhaohui Zou et al. · CA A Cancer Journal for Clinicians · 2014 · 11.6K citations · Full text

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Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

, , +6

Signet-Ring Cell Carcinoma of the Colon: A Case Report and Review of the Literature

Peter Y. Park, Teresa A. Goldin, John C. S. Chang et al. · Case Reports in Oncology · 2015 · 5.3K citations · Full text

, , +17

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

, , +15

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

, , +10