European Neurology · 2008 · 13 citations · 0 references
MedicineNeurologyOphthalmologyElectrophysiologyNeuro-ophthalmologyVisual ElectrophysiologyEvoked PotentialsMultiple SclerosisOptic NerveOptic NeuropathiesVisual Evoked PotentialsVisual SystemClinical History AssessmentElectroretinography FindingsOptic Nerve Pathway DysfunctionOptic Nerve PhysiologyPattern Visual Evoked PotentialsRetinal ElectrophysiologyVisually Evoked PotentialsVoltage
The authors have studied, by means of pattern visual evoked potential (VEP) and flash electroretinogram (ERG) recordings, a group of 15 patients affected by definite multiple sclerosis. All of the subjects examined presented a clinical history indicating involvement of the visual pathways; VEPs were altered in a high percentage of eyes examined (93.3%), while a lower percentage of abnormal ERGs was seen (20% of eyes examined). The only type of ERG alteration found consisted of a pathologic b wave voltage increase, observed mainly with red flash stimuli. This finding could be attributed to an involvement of centrifugal optic nerve fibers having inhibitory functions on retinal cells.