Concepedia

Design and synthesis of a novel three-hindered quadrant bisphosphine ligand and its application in asymmetric hydrogenation

Kexuan Huang, Xiaowei Zhang, Thomas J. Emge, Guohua Hou, Bonan Cao, Xumu Zhang, Xumu Zhang

Chemical Communications · 2010 · 43 citations · 43 references

DOI

Concepts

Abstract

A novel three hindered quadrant bisphosphine ligand has been synthesized. The ligand shows excellent enantioselectivities and reactivities for rhodium-catalyzed hydrogenations of various functionalized olefins.

References

43

BINAP: an efficient chiral element for asymmetric catalysis

Ryōji Noyori, Hidemasa Takaya · Accounts of Chemical Research · 1990 · 1.3K citations

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Asymmetric Hydrogenations (Nobel Lecture) Copyright© The Nobel Foundation 2002. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.

William S. Knowles · Angewandte Chemie International Edition · 2002 · 1.1K citations

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Synthesis of 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl (BINAP), an atropisomeric chiral bis(triaryl)phosphine, and its use in the rhodium(I)-catalyzed asymmetric hydrogenation of .alpha.-(acylamino)acrylic acids

Akira Miyashita, Arisa Yasuda, Hidemasa Takaya et al. · Journal of the American Chemical Society · 1980 · 999 citations

, , +10

Asymmetric Hydrogenations (Nobel Lecture 2001)

William S. Knowles · Advanced Synthesis & Catalysis · 2003 · 943 citations

, , +11

Asymmetric hydrogenation

William S. Knowles · Accounts of Chemical Research · 1983 · 737 citations

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