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Role of PI3K/Akt and MEK/ERK in Mediating Hypoxia-Induced Expression of HIF-1α and VEGF in Laser-Induced Rat Choroidal Neovascularization

DOIFull Paper Access

151

Citations

26

References

2009

Year

Xiumei Yang, Yusheng Wang, Jian Zhang, Yan Li, Jianfeng Xu, Jie Zhu, Wei Zhao, Dake Chu, Peter Wiedemann
Investigative Ophthalmology & Visual Science

Abstract

The PI3K/Akt pathway was required for hypoxia-induced expression of HIF-1alpha and VEGF, whereas the MEK/ERK pathway was required only for VEGF in laser-induced rat CNV.

References

YearCitations

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