Variability of the <i>bla</i> _IMP-15 -Containing Integrons, Highly Related to In <i>95</i> , on an Endemic Clone of <i>Pseudomonas aeruginosa</i> in Mexico

Abstract

The acquisition of β-lactamases, such as class B metallo-β-lactamases, in Pseudomonas aeruginosa is detrimental to antimicrobial therapy in hospitalized patients. In Mexico, metallo-β-lactamase IMP-15 has been found to be encoded on the In95 class 1 integron in a major clone of P. aeruginosa. In this work, we describe the variability of this class 1 integron in an epidemic clone of carbapenem-resistant P. aeruginosa clinical isolates highly related to isolates previously described in Mexico.