Gold(I)‐Catalyzed Unprecedented Rearrangement Reaction Between 2‐Aminobenzaldehydes with Propargyl Amines: An Expedient Route to 3‐Aminoquinolines

Abstract

Access to aminoquinolines: a gold(I)-catalyzed unprecedented rearrangement reaction between 2-aminobenzaldehydes with propargyl amine was studied. The study provided, for the first time, direct access to 3-aminoquinolines in one step starting from readily available starting materials. Elegantly designed experiments were employed to unravel the mechanism of this unprecedented rearrangement, which are corroborated by DFT calculations.