New Target Genes for NOV/CCN3 in Chondrocytes: <i>TGF-β2</i> and <i>Type X Collagen</i>

Abstract

This study provides the first characterization of two new targets of NOV involved in chondrocyte differentiation, shows that NOV acts with TGF-beta1 in a cascade of gene regulation, and indicates that NOV is a positive modulator of chondrogenesis.