The effect of new potent selective inhibitors of protein kinase C on the neutrophil respiratory burst

Inositol trisphosphate, a novel second messenger in cellular signal transduction

Michael J. Berridge, Robin F. Irvine · Nature · 1984 · 6.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Potent selective inhibitors of protein kinase C

Peter D. Davis, Christopher H. Hill, Elizabeth Keech et al. · FEBS Letters · 1989 · 478 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +12

The action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombin

Steve P. Watson, J McNally, Lorna J. Shipman et al. · Biochemical Journal · 1988 · 218 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor.

Craig Gerard, Linda C. McPhail, Anthony Marfat et al. · Journal of Clinical Investigation · 1986 · 213 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Increased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulation.

James E. Smolen, Helen M. Korchak, Gerald Weissmann · Journal of Clinical Investigation · 1980 · 186 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14