Mechanical loading of mouse caudal vertebrae increases trabecular and cortical bone mass-dependence on dose and genotype

Direct Three-Dimensional Morphometric Analysis of Human Cancellous Bone: Microstructural Data from Spine, Femur, Iliac Crest, and Calcaneus

T. Hildebrand, Andres Laib, Ralph Müller et al. · Journal of Bone and Mineral Research · 1999 · 1.3K citations

Medicine, Anatomy, Orthopaedic Surgery +17

Regulation of bone mass by mechanical strain magnitude

Clinton T. Rubin, Lance E. Lanyon · Calcified Tissue International · 1985 · 1.3K citations

Medicine, Bioengineering, Biomedical Engineering +14

Loss of Osteocyte Integrity in Association with Microdamage and Bone Remodeling After Fatigue In Vivo

Olivier Verborgt, Gary Gibson, Mitchell B. Schaffler · Journal of Bone and Mineral Research · 2000 · 727 citations · Full text

Medicine, Cell Biology, Molecular Biology +17

The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents.

Harold M. Frost · PubMed · 1987 · 618 citations

Natural Sciences, Orthopedic Surgery, Physiology +16

Peripheral cannabinoid receptor, CB2, regulates bone mass

Orr Ofek, Meliha Karsak, Nathalie Leclerc et al. · Proceedings of the National Academy of Sciences · 2006 · 531 citations · Full text

Medicine, Pharmacology, Bone Metabolism +16