Anesthesia & Analgesia · 2010 · 12 citations · 5 references
MedicineAnesthesiologyImmunologyAllergyAnesthesiaGeneral AnesthesiologyAnesthesia MalpracticeAnesthesia SafetyDrug AllergyNeuromuscular BlockadeNeuromuscular Blocking AgentsAnaphylaxis To Neuromuscular Blocking AgentsIntradermal Allergy TestingIntradermal Skin TestingOccupational Exposure ManagementOccupational Exposure To Anesthetic GasesPersonal Protective EquipmentSensitivity To Neuromuscular Blocking AgentsSevere Allergic Reaction
We report a case of a final-year anesthesiology trainee who developed a severe allergic reaction to cutaneous exposure of succinylcholine. Intradermal testing was strongly positive to succinylcholine and all the aminosteroid neuromuscular blocking drugs (NMBDs). Specific immunoglobulin E to succinylcholine was also strongly positive. This unusual case of an anesthesiologist acquiring an allergy to an NMBD through occupational exposure has a significant effect on his practice of anesthesia. However, by avoiding operating rooms with a high usage of NMBDs and by wearing personal protective equipment, the anesthesiologist has worked in clinical anesthesia without incident.
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Life-Threatening Anaphylactoid Reactions to Muscle Relaxants
M. McD. Fisher, Ian Munro · Anesthesia & Analgesia · 1983 · 109 citations
Erik Florvaag, S. G. O. Johansson · Immunology and Allergy Clinics of North America · 2009 · 78 citations
Cross-reactivity of rocuronium with other neuromuscular blocking agents.
M C Laxenaire, Isabelle Gastin, D A Moneret-Vautrin et al. · PubMed · 1995 · 68 citations