Concepedia

Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers

Michael Bucher, G. Mair, Frieder Kees

European Journal of Clinical Pharmacology · 2001 · 16 citations · 11 references

DOI

Concepts

References

11

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole*

Pertti J. Neuvonen, Teemu Kantola, Kari T. Kivistö · Clinical Pharmacology & Therapeutics · 1998 · 403 citations

, , +11

Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations*

Teemu Kantola, Kari T. Kivistö, Pertti J. Neuvonen · Clinical Pharmacology & Therapeutics · 1998 · 283 citations

, , +13

Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid*

Teemu Kantola, Kari T. Kivistö, Pertti J. Neuvonen · Clinical Pharmacology & Therapeutics · 1998 · 276 citations

, , +8

Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid

Pertti J. Neuvonen, Kirsi-Maija Jalava · Clinical Pharmacology & Therapeutics · 1996 · 240 citations

, , +13

Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin

Johanna Lilja · Clinical Pharmacology & Therapeutics · 2000 · 185 citations

, , +10