Helvetica Chimica Acta · 1971 · 27 citations · 18 references
Natural SciencesBiochemistryChemistryAnalytical ChemistryChemical KineticsPhysical ChemistryAntimicrobial Drug InteractionsCalorimetryDrug Interactions With AntimicrobialsMichaelis-menten KineticsDrug-ion InteractionEquilibriumEquilibrium Binding ConstantEquilibrium Dissociation ConstantThermodynamic MeasurementsThermodynamic Modeling
Abstract Δ H °, Δ G °, and Δ S ° — and thereby the equilibrium constant of the interaction of carrier antibiotics with ions — are determined using a microcalorimeter on‐line with a dedicated computer. Thermodynamic data of the interaction of monensin, macrotetrolides and valinomycin with sodium and potassium ions in methanol at 25°C are given.
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