Turnover and Distribution of Intravenously Administered Mannose-Terminated Human Acid β-Glucosidase in Murine and Human Tissues

Replacement Therapy for Inherited Enzyme Deficiency — Macrophage-Targeted Glucocerebrosidase for Gaucher's Disease

Norman W. Barton, Roscoe O. Brady, James M. Dambrosia et al. · New England Journal of Medicine · 1991 · 1.3K citations · Full text

Life Sciences, Biochemistry, Pharmacotherapy +17

Evidence for receptor-mediated binding of glycoproteins, glycoconjugates, and lysosomal glycosidases by alveolar macrophages.

Philip D. Stahl, Jane Somsel Rodman, M.J. Miller et al. · Proceedings of the National Academy of Sciences · 1978 · 592 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Enzyme Therapy in Type 1 Gaucher Disease: Comparative Efficacy of Mannose-Terminated Glucocerebrosidase from Natural and Recombinant Sources

Gregory A. Grabowski · Annals of Internal Medicine · 1995 · 448 citations

Life Sciences, Biochemistry, Hematology +14

An electron microscope autoradiographic study of the carbohydrate recognition systems in rat liver. I. Distribution of 125I-ligands among the liver cell types.

A L Hubbard, Glynn Wilson, Gilbert Ashwell et al. · The Journal of Cell Biology · 1979 · 313 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Human β-glucuronidase: In vivo clearance and in vitro uptake by a glycoprotein recognition system on reticuloendothelial cells

Daniel T. Achord, Frederick E. Brot, C. Elliott Bell et al. · Cell · 1978 · 226 citations

Life Sciences, Biochemistry, Pharmacokinetics +3