Colon-Specific Prodrugs of 5-Aminosalicylic Acid: Synthesis and In Vitro/In Vivo Properties of Acidic Amino Acid Derivatives of 5-Aminosalicylic Acid

A polymeric drug for treatment of inflammatory bowel disease

Joseph P. Brown, Geoff V. McGarraugh, Thomas M. Parkinson et al. · Journal of Medicinal Chemistry · 1983 · 149 citations

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Oral colon-specific drug delivery

Željka Pavelić, Biljana Nigović, Petra Konosić et al. · 2006 · 110 citations

Pharmacy, Pharmacology, Pharmacotherapy +10

Intestinal Metabolism and Transport of 5-Aminosalicylate

S.Y. Zhou, David Fleisher, Li‐Heng Pao et al. · Drug Metabolism and Disposition · 1999 · 98 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Nephrotic syndrome after treatment with 5-aminosalicylic acid

Ben Novis, Z. Korzets, P Chen et al. · BMJ · 1988 · 94 citations · Full text

Medicine, Pediatrics, Surgery +10

Release of 5‐aminosalicylic acid from bioadhesive <i>N</i>‐(2‐hydroxypropyl)methacrylamide copolymers by azoreductases <i>in vitro</i>

Pavla Kopečková, Jindŕich Kopec̆ek · Die Makromolekulare Chemie · 1990 · 84 citations

Natural Sciences, Biochemistry, Biotechnology +11