Caries Research · 2008 · 147 citations · 27 references
DentistryOral BiologyOral Health SciencesChild Oral HealthOral MicrobiologyPediatric Dental CariesCaries EpidemiologyCaries EtiologyCaries MicrobiologyCaries PreventionMicrobiology Of Dental CariesSalivary Factors In CariesCaries Experience MeasurementCaries Severity IndicesDental Caries ExperienceDental Caries SeverityOral Streptococci In PlaqueSalivary Predictors Of CariesSevere Early Childhood CariesStreptococcus Mutans Colonization
The aim of this study was to examine the colonization of Streptococcus mutans and Streptococcus sanguinis in the oral cavity and the association with severe early childhood caries (S-ECC). Saliva and plaque samples were collected from 14 S-ECC children and 8 caries-free (CF) children. All S-ECC children were S. mutans positive; 100% of CF children and 93% of S-ECC children were S. sanguinis positive. The children's caries severity was positively correlated with levels of S. mutans (p < 0.001), total oral streptococci (p < 0.01), total cultivable oral bacteria (p < 0.05), and children's age (p < 0.05). Logistic regression analysis showed that the interaction of S. sanguinis with S. mutans was a significant factor associated with the caries status in children, suggesting that the relative levels of these two microorganisms in the oral cavity play an important role in caries development.
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Molecular Analysis of Bacterial Species Associated with Childhood Caries
Mitzi R. Becker, Bruce J. Paster, Eugene J. Leys et al. · Journal of Clinical Microbiology · 2002 · 741 citations · Full text