Synthesis of 4‐aroyl‐5‐nitro‐1<i>H</i>‐imidazoles and 4‐aroyl‐5‐aminoimidazoles

Abstract

Abstract The reaction of α‐(aryl)‐4‐morpholineacetonitriles (masked aroyl anion equivalents) with N ‐protected 4(5)‐bromo‐5(4)‐nitro‐1 H ‐imidazoles gave 4‐aroyl‐5‐nitroimidazoles which were reduced to afford 4‐aroyl‐5‐aminoimidazoles.