Addition of α-Ketoglutarate to Blood Cardioplegia Improves Cardioprotection

Warm induction of cardioplegia with glutamate-enriched blood in coronary patients with cardiogenic shock who are dependent on inotropic drugs and intra-aortic balloon support

Eliot R. Rosenkranz, Gerald D. Buckberg, Hillel Laks et al. · Journal of Thoracic and Cardiovascular Surgery · 1983 · 164 citations

Medicine, Cardiology, Internal Medicine +10

α-ketoglutarate and postoperative muscle catabolism

Jan Wernerman, Folke Hammarqvist, E. Vinnars · The Lancet · 1990 · 126 citations

Medicine, Perioperative Medicine, Surgery +5

The role of the citric acid cycle in cells of the immune system and its importance in sepsis, trauma and burns.

Eric A. Newsholme, Philip Newsholme, Rui Curi · PubMed · 1987 · 122 citations

Life Sciences, Cell Biology, Immunology +17

Trauma metabolism and the heart. Uptake of substrates and effects of insulin early after cardiac operations.

Sveneric Svensson, Rolf Svedjeholm, Rolf Ekroth et al. · PubMed · 1990 · 98 citations

Life Sciences, Endocrinology, Physiology +13

Reversal of ischemic damage with amino acid substrate enhancement during reperfusion.

Lazar Hl, Buckberg Gd, Manganaro Aj et al. · PubMed · 1980 · 93 citations

Life Sciences, Biochemistry, Pharmacology +7