Continuous infusion of frusemide in refractory oedema.

Abstract

Continuous infusion of frusemide in refractory oedemaFrusemide is a potent loop diuretic with an impressive dose-response relationship over a wide dose range.Nevertheless, probably because of concern over possible toxicity,' the attainment of an effective dose may be delayed in patients with oedema refractory to conventional dosing.We report here the frequency with which high-dose frusemide was prescribed in a group of medical inpatients and then describe a small series of patients who were given continuous infusion of frusemide using a constant infusion pump.