Intermittent hypoxia-induced rat pancreatic β-cell apoptosis and protective effects of antioxidant intervention

Abstract

Taken together, these results demonstrate a critical role of oxidative stress in the regulation of apoptosis through Bcl-2 and Bax signaling. The antioxidant NAC has a protective effect against IH-induced pancreatic β-cell apoptosis.Nutrition & Diabetes advance online publication, __PUBDATE__; doi:10.1038/nutd.2014.28.