Detection of R337H, a germline TP53 mutation predisposing to multiple cancers, in asymptomatic women participating in a breast cancer screening program in Southern Brazil

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.4K citations · Full text

Chromatin, Dna Sequencing, Molecular Biological Method +11

A cancer family syndrome in twenty-four kindreds.

Frederick P. Li, Joseph F. Fraumeni, J. J. Mulvihill et al. · PubMed · 1988 · 1.3K citations

Blood Relatives, Cancer Risk, Cancer Pathology +12

The IARC TP53 database: New online mutation analysis and recommendations to users

Magali Olivier, Rosalind A. Eeles, Monica Hollstein et al. · Human Mutation · 2002 · 1.3K citations

An inherited <i>p53</i> mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

Raul C. Ribeiro, Fabiano Sandrini, Bonald C. Figueiredo et al. · Proceedings of the National Academy of Sciences · 2001 · 530 citations · Full text

Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families

Birch, Hartley, Tricker et al. · Cancer Research · 1994 · 478 citations

Constitutional Mutations, Somatic Variant, Genetic Disorder +8