Science · 1994 · 924 citations · 36 references
AgricultureGeneticsPlant BiologyPlant GeneticsPlant Molecular BiologyPlant-microbe InteractionsPlant Defense ResponsesPlant Disease ResistancePlant Immune ResponsesPlant Immune SignalingPlant PathogenesisPlant-pathogen InteractionsPathogen Resistance GenesPlant Defense ActivationPlant Defense InductionPlant Defense MechanismsPlant Disease Resistance GenesPlant Disease Resistance MechanismsPlant Receptor-like KinasesPlant Resistance Genes
The Cf‑9 gene confers resistance to Cladosporium fulvum races carrying Avr9 and encodes a protein homologous to receptor‑like kinases, antifungal polygalacturonase‑inhibiting proteins, and leucine‑rich repeat family members. Cf‑9 was isolated by transposon tagging using the maize Dissociation element. Its DNA sequence encodes a putative membrane‑anchored extracytoplasmic glycoprotein whose structure is consistent with a receptor that could bind Avr9 and trigger plant defense.
The tomato Cf-9 gene confers resistance to infection by races of the fungus Cladosporium fulvum that carry the avirulence gene Avr9 . The Cf-9 gene was isolated by transposon tagging with the maize transposable element Dissociation . The DNA sequence of Cf-9 encodes a putative membrane-anchored extracytoplasmic glycoprotein. The predicted protein shows homology to the receptor domain of several receptor-like protein kinases in Arabidopsis , to antifungal polygalacturonase-inhibiting proteins in plants, and to other members of the leucine-rich repeat family of proteins. This structure is consistent with that of a receptor that could bind Avr9 peptide and activate plant defense.
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Basic local alignment search tool
Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations
A new method for predicting signal sequence cleavage sites
Gunnar von Heijne · Nucleic Acids Research · 1986 · 4.6K citations · Full text