The Journal of Clinical Endocrinology & Metabolism · 1975 · 55 citations · 0 references
MedicineEndocrinologyPharmacotherapyClinical BiochemistryClinical PharmacologyEndocrine PharmacotherapyDiabetes ManagementGlycemic ControlGrowth HormoneGrowth Hormone TherapyPituitary DisordersPituitary HormonesActive Disease DifferentiationBromocriptine TreatmentGrowth Hormone FunctionImpaired Glucose ToleranceNormal Tissue Tolerance
Four men and 4 women with active acromegaly were treated with bromocryptine for 4 to 5 weeks. Serum growth hormone levels response to a glucose load were measured before and in the last weed of treatment. In only 1 patient was the grwotoh hormone response rendered normal by the drug. This patient, but none of the others, also showed an improvement in glucose tolerance and a reductin of the raised serum insulin levels during the glucose load. In three of the 8 patients vomiting was troublesome side effect of treatment.