In vivo genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in lacI transgenic (Big Blue®) mice

The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides

Makoto Hayashi, Takeshi Morita, Yukio Kodama et al. · Mutation Research Letters · 1990 · 510 citations

Medicine, Cell Biology, Pathology +8

Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo.

Jan A. Gossen, W J de Leeuw, C.H. Tan et al. · Proceedings of the National Academy of Sciences · 1989 · 493 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice.

Steven W. Kohler, Gabrielle S. Le Provost, Annabeth Fieck et al. · Proceedings of the National Academy of Sciences · 1991 · 473 citations

Life Sciences, Genetics, Molecular Genetics +15

Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target.

John Jakubczak, Glenn Merlino, John E. French et al. · Proceedings of the National Academy of Sciences · 1996 · 214 citations

Medicine, Genetics, Oncology +17

Other transgenic mutation assays: A new transgenic mouse mutagenesis test system using Spi− and 6-thioguanine selections

T. Nohmi, Masaya Katoh, Hiroshi Suzuki et al. · Environmental and Molecular Mutagenesis · 1996 · 213 citations

Life Sciences, Biotechnology, Genetics +17