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A Case with Euprolactinemic Galactorrhea Induced by Escitalopram
25
Citations
4
References
2007
Year
GastroenterologyPathologyPharmacotherapySerotonin-enhancing AntidepressantsEuprolactinemic Galactorrhea InducedNeuroendocrine MechanismEndocrine MechanismSsri EscitalopramNeuropharmacologyEndocrinologyPharmacologyReproductive Side EffectsPathogenesisPhysiologyNeuroendocrine DisorderExperimental TherapeuticClinical PharmacologyBiological PsychiatryMedicine
Endocrine and reproductive side effects of serotonergic antidepressants are uncommon and galactorrhea is only rarely mentioned among SSRI-related side effects. Perhaps through suppression of dopamine neurotransmission releasing prolactin from tonic inhibitor control of dopamine, serotonin-enhancing antidepressants may result in a rise in prolactin levels. However, we here describe a case of euprolactinemic galactorrhea induced by the SSRI escitalopram and discuss potential mechanisms of action.
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