Neue β‐Lactam‐Antibiotika. Über die Darstellung und Decarbonylierung von 3‐Formylcephem‐Verbindungen. Modifikationen von Antibiotica, 12. Mitteilung [1]

Abstract

Abstract Benzhydrylic esters of 3‐unsubstituted cephem‐4‐carboxylic acids of types 9 and 10 ( Scheme 2 ) are prepared by decarbonylation of esters of 3‐formylcephem compounds of type 2 with tris‐triphenylphosphine‐rhodium chloride. The preparation of the starting materials 2 and 5 , as well as of the nucleus 13 is described.