Concepedia

A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

Emilie D. Smith, N. Ariane Vinson, Desong Zhong, Bertold Berrang, Jennifer L. Catanzaro, James B. Thomas, Hernán A. Navarro, Brian P. Gilmour, Jeffrey R. Deschamps, F. Ivy Carroll

Bioorganic & Medicinal Chemistry · 2007 · 10 citations · 18 references

DOI

Concepts

References

18

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

Jean‐Claude Meunier, Catherine Mollereau, Lawrence Toll et al. · Nature · 1995 · 1.9K citations

, , +14

ORL1, a novel member of the opioid receptor family

Catherine Mollereau, Marc Parmentier, Pierre Mailleux et al. · FEBS Letters · 1994 · 1.1K citations

, , +17

Orphanin FQ is a functional anti-opioid peptide

Jeffrey S. Mogil, Judith E. Grisel, Rainer K. Reinscheid et al. · Neuroscience · 1996 · 378 citations

, , +10

Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress

François Jenck, Jean‐Luc Moreau, James R. Martin et al. · Proceedings of the National Academy of Sciences · 1997 · 348 citations

, , +15

Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors

Toshiya Manabe, Yukihiro Noda, Takayoshi Mamiya et al. · Nature · 1998 · 310 citations

, , +14