Histopathological Diagnosis of Primary Aldosteronism Using CYP11B2 Immunohistochemistry

Abstract

The present study clearly demonstrates that CYP11B2 immunostaining is a powerful tool for histopathological diagnosis of aldosterone overproduction in PA and for subtype classification of APA, multiple APCCs, unilateral multiple adrenocortical micronodules, and diffuse hyperplasia.