Quarterly Journal of Experimental Physiology and Cognate Medical Sciences · 1959 · 48 citations · 0 references
MedicineNeurological SurgeryNeurosurgeryNeuroanatomyNeurophysiologyPeripheral Nerve SurgeryNerve RegenerationNerve RepairNeuromuscular ChangesPeripheral Nerve InjuryPeripheral Nervous SystemPeripheral Nervous System PhysiologyPeripheral Nerve Physiology
In the hindlimb of cats one of a pair of muscle nerves was cut, and changes in function of the central portion studied in vitro and in situ after intervals of 6-40 days; the other nerve served as a control.There was a statistically significant reduction in the conduction velocity and the rate of recovery of the cut nerves.The cut nerves also showed a decreased ability to conduct impulses at high frequencies of stimulation and were more susceptible to the effect of cold.These functional changes were, to some extent, progressive with time; and may be at least partly reversible when peripheral connexions are again made.Similar changes were seen in a rabbit nerve 50 days after peripheral section.