Dermal fibroblasts are one of the therapeutic targets for topical application of 1α,25‐dihydroxyvitamin D₃: the possible involvement of transforming growth factor‐β induction

Abstract

These results suggest that antiproliferative and anti-inflammatory effects of 1,25(OH)2D3 on psoriatic lesional skin may be mediated, at least in part, by a complex TGF-beta regulation in local dermal fibroblasts.