Angiotensin II Type 2 Receptor Mediates Vascular Smooth Muscle Cell Apoptosis in Cystic Medial Degeneration Associated With Marfan’s Syndrome - Concepedia

Concepedia

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Angiotensin II Type 2 Receptor Mediates Vascular Smooth Muscle Cell Apoptosis in Cystic Medial Degeneration Associated With Marfan’s Syndrome

105

Citations

0

References

2001

Year

Hirotaka Nagashima, Yasunari Sakomura, Yoshikazu Aoka, Kenta Uto, Kin-ichi Kameyama, Motoko Ogawa, Shigeyuki Aomi, Hitoshi Koyanagi, Naoko Ishizuka, Mitsuhide Naruse,

Abstract

Accelerated ACE-dependent Ang II formation and signaling via upregulated AT2R play a pivotal role in VSMC apoptosis in CMD, and the ACE inhibitor could have clinical value in the prevention and treatment of CMD.