Genome-Wide Significance and Replication of the Chromosome 12p11.22 Locus Near the <i>PTHLH</i> Gene for Peripartum Cardiomyopathy

Abstract

Genome-wide association with PPCM was discovered and replicated for rs258415 at chromosome 12p11.22 near PTHLH. This study indicates a role of genetic factors in PPCM and provides a new locus for further pathophysiological and clinical investigation.