Risk Factors for End Stage Renal Disease in Children With Posterior Urethral Valves

Abstract

Patients with posterior urethral valves and severe bladder dysfunction in whom nadir creatinine remains increased are at risk for upper urinary tract deterioration, requiring renal replacement therapy. It is unclear whether high grade vesicoureteral reflux at diagnosis may also be a poor prognostic sign. Further analysis is necessary to evaluate the effects of early aggressive bladder management on renal outcomes.