Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells - Concepedia

Concepedia

Publication | Open Access

Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

DOI Full Paper Access

45

Citations

31

References

2014

Year

Lixian Wu, Jing Yu, Ruijia Chen, Yang Liu, Liguang Lou, Ying Wu, Lisen Huang, Yingjuan Fan, Pinzhang Gao, Meijuan Huang,

Clinical Cancer Research

Abstract

Dual suppression of Abl kinase activity and Hsp90 chaperone function by C086 provides a new therapeutic strategy for treating Bcr-Abl-induced leukemia resistant to TKIs.

References

	Year	Citations

Page 1