THE EFFECTS OF SALT RESTRICTION ON THE RENAL CONCENTRATING OPERATION IN NORMAL, HYDROPENIC MAN*

Abstract

diuresis was established with a hypertonic mannitol infusion in subjects maintained on both high and low salt diets. In those of Group II, subjects prepared as in Group I received intravenous aminophylline during a mannitol diuresis at high levels of solute clearance. In those of Group III, similarly prepared subjects received aminophylline at low levels of solute clearance during a mannitol diuresis. Maximal hydropenia was established in all subjects by