Repeatability of Spectralis OCT Measurements of Macular Thickness and Volume in Diabetic Macular Edema

Abstract

Retinal thickness measurements in subjects with DME obtained using Spectralis OCT are considerably less variable than has been reported with other devices. Changes in central subfield thickness >8 μm can be considered more indicative of true clinical change rather than measurement variability. This finding informs clinical practice and clinical trial design.